The 152nd running of the Kentucky Derby is scheduled for 6:57pm on Saturday from Churchill Downs in Louisville, Kentucky, as 20 of the best three-year old horses in the world compete in the Run for the Roses.

A total of $5 million is on the line for the owners, trainers and jockeys, but more than $234.4 million was wagered on last year’s race. Expect that number to be even bigger in 2026 on what should be a cloudy-but-dry track, as opposed to last year’s questionable weather at Churchill Downs.

The favorite is Renegade, trained by two-time Derby winner Todd Pletcher (2010 Super Saver, 2017 Always Dreaming) with Irad Ortiz Jr. aboard from the rail. The sire of Into Mischief and Spice Is Nice was 0-3 from the chute as a two-year-old, but is undefeated in two starts during 2026. The wins came at the Sam F. Davis Stakes in Tampa, and the Grade I Arkansas Derby where he posted a flashy 107 speed figure in his four-length victory.

Churchill Downs new oddsmaker Nick Tammaro, who replaced the legendary Mike Battaglia earlier this year, has Renegade as the projected 4-1 chalk.

The second choice is Commandment, with Luis Saez aboard the Brad Cox trainee. Another son of Into Mischief, Commandment broke his maiden at Churchill Downs last November 1 in a special weight race. Since then he’s undefeated, winning three stakes races all at Gulfstream Park in South Florida. He took the Florida Derby by a nose over fellow Derby entrant The Puma, paying 5.80 for the win, and is 6-1 on the morning line.

Here are the opening odds, followed by the latest track odds, from Churchill Downs ahead of the 2026 Kentucky Derby.

Updated: May 1, 11:35 p.m.